Too Many Parents Are Blowing It: Kids Need The Nanny State To Require The HPV Vaccine

“This is super important.”
— Dr. Dale

Too Many Parents Are Blowing It: Kids Need The Nanny State To Require The HPV Vaccine

http://www.huffingtonpost.com/ian-reifowitz/too-many-parents-are-blow_b_9349904.html

Ian Reifowitz

The news is good, but it could be so much better. The journal Pediatrics recently published a study that compared the prevalence of the human papillomavirus (HPV) in American girls and young women in the years before and after the HPV vaccine was first recommended in 2006.

 

 

CONCLUSIONS: Within 6 years of vaccine introduction, there was a 64% decrease in 4vHPV type prevalence among females aged 14 to 19 years and a 34% decrease among those aged 20 to 24 years. This finding extends previous observations of population impact in the United States and demonstrates the first national evidence of impact among females in their 20s.

[snip] Although rates of HPV vaccination have been increasing in the United States, coverage is still low; in 2013, a national survey found that 57% of 13- to 17-year-old females had received at least 1 dose and 38% had received 3 doses. [NOTE: The recommendation is for a 3 dose course]

 

 

This is incredibly important because HPV causes some really nasty forms of cancer. For women, just about every case of cervical cancer -- which, according to the CDC, "usually does not have symptoms until it is quite advanced and hard to treat" -- results from HPV. Over 4,000 American women die from it every year. Overall, 18,000 women and 9,000 men get cancer of some kind from HPV (others include cancer of the vulva, vagina, penis, anus, and back of the throat).

Additionally, more than 400,000 American women are diagnosed annually with pre-cancerous cervical lesions resulting from potential HPV infections. These women may undergo multiple cervical biopsies, and many require the removal of a portion of their cervix. This can increase the risk that they will deliver prematurely in the future. Premature birth is the number one risk factor for infant death, and one of the leading causes of brain damage and numerous other health problems in children. Oh, and don't forget that HPV can also lead to genital warts. Lovely.

Additionally, only about 20 percent of boys aged 13 to 17 are immunized. This matters both for their own health, and because boys and girls spread HPV through sexual activity. The previous two words are the ones that largely explain why vaccination rates in the U.S. aren't higher.

 

 

***

 

 

First, doctors aren't recommending the vaccine strongly enough. Here's what a University of North Carolina study found:

 

 

Background: Low human papillomavirus (HPV) vaccination coverage stands in stark contrast to our success in delivering other adolescent vaccines. To identify opportunities for improving physicians' recommendations for HPV vaccination, we sought to understand how the communication context surrounding adolescent vaccination varies by vaccine type.

[snip] Conclusions: Our findings suggest that primary care physicians perceived HPV vaccine discussions to be burdensome, requiring more time and engendering less parental support than other adolescent vaccines. Perhaps for this reason, physicians in our national study recommended HPV vaccine less strongly than other adolescent vaccines, and often chose to discuss it last.

 

 

One young woman's story exemplifies this problem. When Vanessa Laven was a college student and resided in the suburbs near New York City -- not exactly the most conservative of areas -- she made an appointment with her gynecologist and asked for the HPV vaccine. What did her physician say? You don't need it. Why? Because, he said, she's a "good girl" from a "good family." She didn't get the vaccine, and now has to live with the consequences of that paternalistic advice.

 

 

"It was totally about sex," said Laven, now 29, living in Minneapolis with her husband, and, sadly, positive for both HPV and the precancerous cell growth associated with it. "The discussion of the vaccine was tied up with some old-fashioned notion of virtue."

 

 

Then there's the parents. Some parents in this country are simply opposed to vaccines in general, as Mickey Mouse and the rest of us learned the hard way about a year ago. But the specific resistance to HPV vaccination goes far beyond that general anti-vaccine hysteria. As with Vanessa Laven's doctor, it's about sex.

There are some parents who think that their teenagers -- and this applies even more so with girls -- won't have sex and shouldn't have sex and sex is bad and how dare you bring up sex? These are many of the same people who think sex education should consist of teaching abstinence only because anything else will give kids the "wrong idea," and will somehow encourage them to have sex by making it less dangerous. Apparently, these parents think HPV vaccines are just as threatening to their morality as students learning to put a condom on a banana. And they're right -- but not in the way they'd expect.

Research shows that young people who get comprehensive sex education are "not more likely to become sexually active, increase sexual activity, or experience negative sexual health outcomes." The same is true for those who receive an HPV vaccine. A study from the Journal of the American Medical Association (JAMA) found: "Human papillomavirus vaccination was not associated with increases in [sexually transmitted infections] in a large cohort of females." Finally, the HPV vaccines are safe. There have been no documented side effects beyond "brief soreness and other local symptoms at the injection site. These problems are similar to those commonly experienced with other vaccines."

I know, I know, how can science compete with what people know in their gut? All kidding aside, what kind of person says: I know this vaccine might save my children's lives, but -- without any basis in fact -- I think it might encourage them to have sex at a younger age, so I won't let them have it. That's a kind of insanity that I -- a parent of two girls myself -- simply cannot fathom.

There's a pretty high likelihood that, at some point in their lives, my daughters will be sexually active. When that day comes, I couldn't live with myself if I had done anything to increase the risk that they'll die from it. That may not be the way some parents think of their actions, but that is the reality.

As a society we are reluctant to increase the reach of government, to expand its authority in ways that interfere with liberty. That's a sound instinct in general, as government should step in only when actions by private citizens prove ineffective or harmful. And that is the case here. Liberty is one thing, but parents denying their children potentially life-saving medical care is another. The vaccination needs to take place before the onset of sexual activity, as it will not help a person who has already been infected with HPV. That's why the medical community, through the Advisory Committee on Immunization Practices (ACIP), recommends vaccinations begin at age 11-12.

If parents won't get their kids vaccinated on their own, we have to require it for the sake of their children, just as many states do for multiple other vaccines. The least we could do is offer it in schools, like other countries do. Rwanda has a 93 percent HPV immunization rate for girls. Why don't we?

We cannot allow Victorian attitudes held by adults about sex to put their children's health and lives -- disproportionately female lives -- at risk. Call it the nanny state, call it big government, whatever. But let's also call what the anti-HPV vaccine parents are doing to their kids by the right name: child abuse.

A version of this post originally appeared on Daily Kos.

Follow Ian Reifowitz on Twitter: www.twitter.com/ianreifowitz

Migraine Linked to Irritable Bowel Syndrome

“This is very interesting. Many of my patients tell me that gluten/wheat/celiac is one trigger of migraines.

This article intrigued me as a new cause, and it’s interesting because the symptoms of Celiac and IBS are similar.

You can read more about the differences here: http://www.everydayhealth.com/celiac-disease/celiac-disease-and-ibs-differences-and-similarities.aspx”
— Dr. Dale

Migraine Linked to Irritable Bowel Syndrome

Megan Brook
http://www.medscape.com/viewarticle/859763

March 02, 2016

Migraine and tension-type headache may share links with irritable bowel syndrome (IBS), a preliminary study hints.

"Our results suggest a high possibility of phenotypic and genotypic associations between IBS and primary headache disorders (particularly migraine) and support the presence of some shared pathophysiology," Derya Uluduz, MD, from Istanbul University in Turkey, told Medscape Medical News.

"Greater attention should be focused on the comorbidities of these conditions and their potential contribution to better understanding and managing the disorder. Physicians should examine the presence of IBS in migraine and tension-type headache patients or vice versa for accurate management of these disorders," Dr Uluduz added.

The study was released February 23 ahead of presentation in April at the American Academy of Neurology (AAN) 68th Annual Meeting in Vancouver, Canada.

"Migraine of the Bowels"

"In designing this study, we were interested in whether IBS and migraine coexist within a same spectrum of central sensitization syndrome and have phenotypic and genotypic associations," Dr Uluduz explained. "We already knew that brain plays significant role in IBS. IBS may be characterized by dysfunctions in processing of information by the central nervous system. IBS patients have increased hypothalamic activity suggesting an association among IBS, stress and hypothalamic axis. In this respect, IBS may be defined as the 'migraine of the bowels.'"

The study included 107 people with migraine, 53 with episodic tension-type headache (ETTH), 107 with IBS, and 53 healthy individuals. "This is the first study to investigate the relationship between IBS and primary headaches, including ETTH, using a comprehensive face-to-face clinical diagnostic evaluation and information on multiple serotonin transporter gene polymorphisms," Dr Uluduz told Medscape Medical News.

The researchers found that IBS, diagnosed according to strict criteria, occurred in 54.2% of patients with migraine and 28.3% of patients with ETTH. In addition, 35.5% of patients with IBS had migraine and 22.4% had ETTH.

In addition, their analysis of the serotonin transporter gene and the serotonin receptor 2A gene showed that the IBS, migraine, and ETTH groups had at least one gene that differed from the genes of the healthy participants.

Notably, "5-HTTLPR (LL-LS-SS) polymorphisms were found to be higher in patients with migraine and IBS but not in ETTH patients compared to controls," Dr Uluduz said. "The frequency of the 10/12 genotype in the 5-HTT-VNTR genotype was significantly more frequent in patients with migraine, ETTH, and IBS compared to control subjects. The frequency of the 12/12 genotype in the 5-HTT-VNTR genotype tended to be more insignificantly frequent in patients with migraine and IBS but not in ETTH."

The researchers say further studies are needed to explore links between headache disorders and IBS, which could help guide management.

"The effects of antidepressants on IBS and chronic pain syndromes, such as migraine and ETTH, by downregulation of peripheral pain-mediating systems have been demonstrated," Dr Uluduz commented. "Along with genotypic similarities, this indirectly indicates similarities in the central alterations of the serotonergic system in these disorders."

The Brain-Gut Axis

Reached for comment, Teshamae S. Monteith, MD, chief of the Headache Division at the University of Miami's Miller School of Medicine, Florida, said the link is not entirely novel.

"Based on clinical and epidemiological observations, it has long been recognized that migraines and IBS are likely linked," Dr Monteith told Medscape Medical News. "The association is a good example of the brain-gut axis and how it relates to disease. There appears to be a genetic link resulting in disturbances within the serotoninergic neurotransmitter system."

Dr Monteith also thinks it's important to assess for the presence of IBS in headache patients and vice versa for accurate management.

"Often, patients reporting both abdominal pain and headache are labeled as somatic. The study provides further evidence to support the biological vulnerability to pain in patients with primary headache and IBS. Based on these results, the role of treatments that target the brain-gut axis should be further explored. The association between these genes, pain persistence and food sensitivities should also be explored," Dr Monteith said.

The study was supported by Mersin University. The authors have disclosed no relevant financial relationships.

To be presented at the 68th American Academy of Neurology (AAN) Annual Meeting, April 15-21, 2016. Abstract 3367.

 

Medscape Medical News © 2016  WebMD, LLC 

Send comments and news tips to news@medscape.net.

 

 

HRT for elderly men could boost libido and make them happier

“Let me know if you want to be tested for lowT. We have plenty of patients whose lives have been changed with Testosterone Replacement Therapy.

Also, TRT isn’t just for the elderly... anyone can have lowT and all it takes is a simple test. ”
— Dr. Dale

HRT for elderly men could boost libido and make them happier

http://www.telegraph.co.uk/news/health/news/12161822/Hormone-Replacement-Therapy-for-elderly-men-could-boost-sex-drive-and-make-them-happier.html

A 'landmark' new study has suggested that should consider taking hormone replacement therapy to boost their sex drive and improve their moods  

 Men over 65 should consider taking hormone replacement therapy to boost their sex drive and improve their moods, according to new research.

Men who were treated with testosterone were founded to have higher sexual function and better moods than older men with low levels of the sex hormone.

Researchers said the results, published by the New England Journal of Medicine, were the first to convincingly show the benefits of testosterone for men over the age of 65.

The findings of the US study of 790 men led by the University of Pennsylvania is the latest contribution to the long-running debate over the benefits of hormone therapy for men. 

 In 2003 an Institute of Medicine panel concluded that there was insufficient evidence that testosterone treatment was beneficial in older men, calling for more research into the issue.

And while testosterone has previously been explored as a potential treatment for diminished sexual function, mobility, and energy levels in men, the results of previous trials have been inconsistent.

To test the potential benefit of testosterone treatment in men who had low levels of the hormone for no other reason than their advancing age, researchers investigated the effectiveness of testosterone gel for boosting their sexual function, physical function and vitality.

The researchers found that men who received testosterone therapy for a year saw "significant improvements" in sexual function - including sexual activity, sexual desire, and erectile function when compared to those on a placebo.

Study co-author Professor Thomas Gill, of Yale School of Medicine, said: "There appears to be benefits for treatment with testosterone among men who have unequivocally low levels of testosterone that are attributable solely to age.

"The benefits were quite convincing for sexual function." 

 The effects on the patients' physical abilities were not so clear as the subjects specifically tested for improvements in their walking speed did not see significant improvements.

However when all of the study's participants were included, there was a modest performance improvement as measured by an increase of 50 metres or more in the distance patients could walk in six minutes.

Men who had their vitality observed as part of the study saw modest benefits including improved mood and fewer depressive symptoms.

While the results were somewhat mixed, researchers said that an overall benefit that had not been seen in previous studies.

Prof. Gill said: "One way of interpreting the results across trials is a global impression of change.

"We found that testosterone improved men's impression that their sexual desire, walking ability, energy level, and overall health were better."

The researchers also reported that there were no increases in adverse side effects a year after testosterone therapy was discontinued.  

 However, Prof Gill said a larger trial would be needed to conclusively prove safety in the long term.

"The number of participants was too few to draw conclusions about the risk of testosterone treatment," the study's authors warned.

The research has been welcomed as a possible step towards guaranteeing quality of life for older men.

"It is a landmark study in the field of men's health and no doubt a bell-wether for additional important contributions," wrote Dr Eric Orwoll in the New England Journal of Medicine.

"Their report is important, not only because it deals with an essential public health issue but also because the investigators have succeeded in conducting the kind of well-conceived studies that are sorely needed." 

 Do women have it?

Most certainly. It’s very important for controlling a woman’s sexual drive. This is a rather unique function of testosterone in primates.

There may be other important functions in some contexts, but there are not enough studies on testosterone in women. The idea that successful women (in a male sense) have more testosterone is nonsense.

 

Can we control testosterone ?

Much of human society, its laws, inhibitions, customs and traditions are really directed towards the social control of testosterone. Males can’t behave without restraint, much as they might like to do so.

 

What happens to testosterone at midlife and beyond?

Testosterone does decline with age, but at different rates in different males. It can result in erectile dysfunction, though this is not as common as often believed: erectile problems with age are mostly not dependent on testosterone.

However, prescriptions for testosterone supplements have increased three-fold in the UK in the last 10 years so there is clearly a belief that it does some good.